circRNA basic information
circBase ID: hsa_circ_0007534
Name: hsa_circ_DDX42
Synonym: -
Host Gene: hsa-miR-761
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: cell line
Sample type details: human glioma cell lines (U251, U118, LN229, U87MG)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZIC5
Associated microRNA: hsa-miR-761
Biological function: promotes proliferation and migration of glioma cells
Molecular mechanism: promoting ZIC5 expression by repressing hsa-miR-761 availability
Survival: -
Supported No.:
 2
Description:

Our results suggested that hsa_circ_0007534/miR-761/ZIC5 regulatory loop might be a promising therapeutic target for glioma treatment.
Other information
Title:

Hsa_circ_0007534/miR-761/ZIC5 regulatory loop modulates the proliferation and migration of glioma cells.

Journal: Biochem Biophys Res Commun
Published: 2018/4/2
PubMed ID: 29605301