circRNA basic information
circBase ID: -
Name: hsa_circ_MAN2B2
Synonym: -
Host Gene: hsa-miR-1275
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human lung cell line (BESA-2B), lung cancer cell lines (A549, H226, H1299, H446)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXK1
Associated microRNA: hsa-miR-1275
Biological function: facilitates lung cancer cell proliferation and invasion
Molecular mechanism: promoting FOXK1 expression by sponging hsa-miR-1275
Survival: -
Supported No.:
 1
Description:

Taken together, our study demonstrated that circMAN2B2 acts as an oncogenic role in lung cancer through promoting FOXK1 expression by sponging miR-1275.
Other information
Title:

Circular RNA circMAN2B2 facilitates lung cancer cell proliferation and invasion via miR-1275/FOXK1 axis.

Journal: Biochem Biophys Res Commun
Published: 2018/3/20
PubMed ID: 29550475