circRNA basic information
circBase ID: -
Name: hsa_circ_SHKBP1
Synonym: circ-SHKBP1
Host Gene: hsa-miR-544a, hsa-miR-379
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: cell line
Sample type details: human glioblastoma cell line (U87MG), HEK293T cell line
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXP1, FOXP2
Associated microRNA: hsa-miR-544a, hsa-miR-379
Biological function: promote cells proliferation, migration, invasion and metastasis
Molecular mechanism: Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through hsa-miR-544a/FOXP1 and hsa-miR-379/FOXP2 Pathways
Survival: -
Supported No.:
 2
Description:

the present study demonstrated that circ-SHKBP1 regulated the angiogenesis of GECs through miR-544a/FOXP1 and miR-379/FOXP2 pathways, and these findings might provide a potential target and effective strategy for combined therapy of gliomas.
Other information
Title:

circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways.

Journal: Mol Ther Nucleic Acids
Published: 2018/3/4
PubMed ID: 29499945