circRNA basic information
circBase ID: hsa_circ_0007385
Name: hsa_circ_MEMO1
Synonym: -
Host Gene: hsa-miR-485-3p, hsa-miR-543, hsa-miR-337-3p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: ATCC supplied CRC cell lines (SW480, LoVo, HCT-116, Caco-2), human normal colonic epithelial cell line (HCoEpiC)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MEMO1
Associated microRNA: hsa-miR-485-3p, hsa-miR-543, hsa-miR-337-3p
Biological function: Hsa_circ_0007385 silencing inhibited CRC progression
Molecular mechanism: Hsa_circ_0007385/hsa-miR-485-3p/hsa-miR-543/hsa-miR-337-3p/MEMO1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Hsa_circ_0007385 promoted CRC progression via modulating miR-485-3p/miR-543/miR-337-3p/MEMO1 axis. Thus, circ-MEMO1 might be a promising therapeutic target for CRC.
Other information
Title:

MiR-485-3p/MiR-543/MiR-337-3p is Required for the Oncogenic Potential of the Hsa_circ_0007385-MEMO1 Axis in Colorectal Cancer

Journal: Biochem Genet
Published: 2023/8/10
PubMed ID: 37561333