circRNA basic information
circBase ID: hsa_circ_0002402
Name: hsa_circ_ECE1
Synonym: CircECE1
Host Gene: hsa-miR-588
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human osteoblast cell line (hFOB1.19), OS cell lines (MG63, U2OS)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RAB3D
Associated microRNA: hsa-miR-588
Biological function: High levels of circECE1 were positively linked to OS cell viability, proliferation, migration and invasion, and negatively linked to OS cell apoptosis rate.
Molecular mechanism: circECE1/hsa-miR-588/RAB3D axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

We elucidated the function of a novel circECE1/miR-588/RAB3D axis in OS progression.
Other information
Title:

CircECE1 promotes osteosarcoma progression through regulating RAB3D by sponging miR-588

Journal: J Orthop Surg Res
Published: 2023/8/9
PubMed ID: 37559140