circRNA basic information
circBase ID: -
Name: mmu_circ_Epha5
Synonym: CircEpha5
Host Gene: mmu-miR-758-5p
 
 
 
Disease basic information
DO ID:
 11612
DO name: polycystic ovary syndrome
Disease details: polycystic ovary syndrome
Species: mouse
Species details: mouse
Sample type: cell line, PDX
Sample type details: Mouse preantral follicles were extracted from the ovaries of 3-week-old mice
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: Cyp17a1
Associated microRNA: mmu-miR-758-5p
Biological function: promoting the synthesis and secretion of androgen in the preantral follicles.
Molecular mechanism: circEpha5 could sponge miR-758-5p to regulate the expression of_yp17a1
Survival: -
Supported No.:
 1
Description:

This work is contributed to the understanding of the pathogenesis of hyperandrogenemia and lays the foundation for the development of therapeutic targets of PCOS hyperandrogenism.
Other information
Title:

CircEpha5 regulates the synthesis and secretion of androgen in mouse preantral follicles by targeting miR-758-5p.

Journal: J Obstet Gynaecol
Published: 2023/8/9
PubMed ID: 37555585