circRNA basic information
circBase ID: hsa_circ_0010889
Name: hsa_circ_PITHD1
Synonym: -
Host Gene: hsa-miR-590-5p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: brain glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human glioma cell lines (LN229, SHG44, U251, T98G), normal glial cell lines (HEB)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: SATB1
Associated microRNA: hsa-miR-590-5p
Biological function: Downregulation of hsa_circ_0010889 inhibited glioma invasion and proliferation in both in vitro and in vivo
Molecular mechanism: hsa_circ_0010889/hsa-miR-590-5p/SATB1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Taken together, our study demonstrates that hsa_circ_0010889 downregulation inhibits glioma progression through the miR-590-5p/SATB1 axis.
Other information
Title:

hsa_circ_0010889 downregulation inhibits malignant glioma progression by modulating the miR-590-5p/SATB1 axis

Journal: Aging (Albany NY)
Published: 2023/8/3
PubMed ID: 37540226