circRNA basic information
circBase ID: hsa_circ_0090231
Name: hsa_circ_USP9X
Synonym: circ_0090231
Host Gene: hsa-miR-942-5p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human aortic VSMCs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PPM1B
Associated microRNA: hsa-miR-942-5p
Biological function: Functionally, silencing of circ_0090231 could reverse ox-LDL-induced proliferation, migration and invasion in VSMCs.
Molecular mechanism: circ_0090231/hsa-miR-942-5p/PPM1B axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

Silencing of circ_0090231 could reverse ox-LDL-induced proliferation, migration and invasion in VSMCs via miR-942-5p/PPM1B axis, providing a theoretical basis for elucidating the mechanism of AS process.
Other information
Title:

Circ_0090231 knockdown protects vascular smooth muscle cells from ox-LDL-induced proliferation, migration and invasion via miR-942-5p/PPM1B axis during atherosclerosis

Journal: Mol Cell Biochem
Published: 2023/7/29
PubMed ID: 37515673