circRNA basic information
circBase ID: hsa_circ_0005654
Name: hsa_circ_PRDM5
Synonym: -
Host Gene: hsa-miR-25-3p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal MCF-10A cells, BC cells (MCF-7, MDA-MB-231)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: ANKRD46
Associated microRNA: hsa-miR-25-3p
Biological function: Overexpression of circ_PRDM5 suppressed proliferation and motility but enhanced apoptosis of BC cells.
Molecular mechanism: Circ_PRDM5/hsa-miR-25-3p/ANKRD46 axis
Survival: -
Supported No.:
 1
Description:

This study evidenced that circ_PRDM5 inhibited cell progression and tumor growth in BC via interacting with mir-25-3p/ANKRD46 network.
Other information
Title:

Circ_PRDM5/miR-25-3p/ANKRD46 axis is associated with cell malignant behaviors in subjects with breast cancer evaluated by ultrasound

Journal: J Biochem Mol Toxicol
Published: 2023/7/23
PubMed ID: 37485755