circRNA basic information
circBase ID: -
Name: hsa_circ_BBS9
Synonym: -
Host Gene: hsa-miR-103a-3p
 
 
 
Disease basic information
DO ID:
 3083
DO name: chronic obstructive pulmonary disease
Disease details: chronic obstructive pulmonary disease
Species: human
Species details: human
Sample type: cell line
Sample type details: human pulmonary microvascular endothelial cells (HPMECs), 293T cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: BCL2L13
Associated microRNA: hsa-miR-103a-3p
Biological function: The level of circRNA BBS9 increased in 1% CSE-induced cells, and silencing of circRNA BBS9 decreased the ratio of apoptotic cells among the 1% CSE-induced HPMECs.
Molecular mechanism: circ_BBS9/hsa-miR-103a-3p/BCL2L13 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

circRNA BBS9 is involved in COPD development as it inhibits the functioning of miRNA-103a-3p. Our results suggest that circRNA BBS9 may act as a novel target for treating COPD.
Other information
Title:

Significant role of circRNA BBS9 in chronic obstructive pulmonary disease via miRNA-103a-3p/BCL2L13

Journal: BMC Pulm Med
Published: 2023/7/13
PubMed ID: 37442983