circRNA basic information
circBase ID: hsa_circ_0067934
Name: -
Synonym: circ_0067934
Host Gene: hsa-miR-1324
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HCC cell lines (BEL7402, Hep3B, HuH7, MHCC97-L), human normal hepatic cell line (HL-7702)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FZD5
Associated microRNA: hsa-miR-1324
Biological function: enhanced the proliferation, migration and invasion of HCC cells
Molecular mechanism: inhibition of hsa-miR-1324 and concomitant activation of FZD5/Wnt/beta-catenin signaling pathway
Survival: -
Supported No.:
 2
Description:

the circ_0067934/miR-1324/FZD5/beta-catenin signaling axis might serve as a promising therapeutic target for HCC intervention.
Other information
Title:

CircRNA circ_0067934 promotes tumor growth and metastasis in hepatocellular carcinoma through regulation of miR-1324/FZD5/Wnt/beta-catenin axis.

Journal: Biochem Biophys Res Commun
Published: 2018/2/20
PubMed ID: 29458020