circRNA basic information
circBase ID: hsa_circ_0002003
Name: hsa_circ_KIAA0146
Synonym: -
Host Gene: hsa-miR-1343-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: liver cancer cell lines (HepG2, Hep3B, Huh7, SNU-387, MHCC97H)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: DTYMK, DAP3, STMN1
Associated microRNA: hsa-miR-1343-3p
Biological function: Our in vitro data indicated that upregulation of hsa_circ_0002003 accelerated cell growth and metastasis
Molecular mechanism: hsa_circ_0002003/hsa-miR-1343-3p/STMN1, miRNA sponge
Survival: poor
Supported No.:
 1
Description:

Hsa_circ_0002003 may play critical roles in HCC pathogenesis and serve as a potential prognostic biomarker for HCC. Targeting the hsa_circ_0002003/hsa-miR-1343-3p/STMN1 regulatory axis could be an effective therapeutic strategy in patients with HCC.
Other information
Title:

Upregulation of hsa_circ_0002003 promotes hepatocellular carcinoma progression

Journal: BMC Cancer
Published: 2023/7/3
PubMed ID: 37400785