circRNA basic information
circBase ID: hsa_circ_0005615
Name: hsa_circ_NFATC3
Synonym: circNFATC3
Host Gene: hsa-miR-520h
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human OSCC cell lines (SCC25, HSC3, SCC15)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: LDHA
Associated microRNA: hsa-miR-520h
Biological function: circNFATC3 knockdown repressed the cell glycolysis metabolism, cell proliferation, migration, and invasion, although it improved cell apoptosis in OSCC cells
Molecular mechanism: circNFATC3/hsa-miR-520h/LDHA axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

In conclusion, circNFATC3 promoted the advancement of OSCC by adjusting the miR-520h/LDHA axis.
Other information
Title:

circNFATC3 facilitated the progression of oral squamous cell carcinoma via the miR-520h/LDHA axis.

Journal: Open Med (Wars)
Published: 2023/7/3
PubMed ID: 37398901