circRNA basic information
circBase ID: hsa_circ_0001791
Name: hsa_circ_ADAM9
Synonym: circADAM9
Host Gene: hsa-miR-1236-3p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: BC cells (MDA-MB-468, SKBR3, BT549, MCF-7, MDA-MB-231), normal human breast epithelial cell line (MCF-10A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FGF7
Associated microRNA: hsa-miR-1236-3p
Biological function: circADAM9 silencing inhibited BC cell proliferation, migration, invasion, and glycolysis, and promoted cell apoptosis
Molecular mechanism: CircADAM9/hsa-miR-1236-3p/FGF7 axis, miRNA sponge
Survival: -
Supported No.:
 3
Description:

CircADAM9 promoted BC development partly by the miR-1236-3p/FGF7 axis, highlighting a potential prognostic biomarker and therapeutic target for BC patients.
Other information
Title:

Knockdown of circADAM9 inhibits cell progression and glycolysis by targeting the miR-1236-3p/FGF7 axis in breast cancer.

Journal: Thorac Cancer
Published: 2023/6/30
PubMed ID: 37385973