circRNA basic information
circBase ID: hsa_circ_0035292
Name: -
Synonym: circ_0035292
Host Gene: hsa-miR-370-3p
 
 
 
Disease basic information
DO ID:
 552
DO name: pneumonia
Disease details: pneumonia
Species: human
Species details: human
Sample type: cell line
Sample type details: Wistsar Institute (WI)-38 cells.
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TBL1XR1
Associated microRNA: hsa-miR-370-3p
Biological function: Circ_0035292 knockdown rescued LPS-mediated WI-38 cell proliferation suppression and WI-38 cell apoptosis and inflammation promotion.
Molecular mechanism: Circ_0035292 interacted with miR-370-3p and miR-370-3p directly targeted TBL1XR1.
Survival: -
Supported No.:
 3
Description:

Knockdown of circ_0035292 rescued LPS-triggered WI-38 cell injury via miR-370-3p/TBL1XR1 axis and NF-¦ĘB pathway.
Other information
Title:

Circ_0035292 knockdown alleviates lipopolysaccharide (LPS)-induced WI-38 cell apoptosis and inflammatory injury.

Journal: Immun Inflamm Dis
Published: 2023/6/29
PubMed ID: 37382271