circRNA basic information
circBase ID: hsa_circ_0008732
Name: hsa_circ_BNC2
Synonym: circBNC2
Host Gene: hsa-miR-217
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: L02, Huh7, HCCLM3, Hep3B
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGA2
Associated microRNA: hsa-miR-217
Biological function: Knockdown of circBNC2 inhibited the HCC progression
Molecular mechanism: circBNC2/hsa-miR-217/HMGA2 axis, miRNA sponge
Survival: poor
Supported No.:
 1
Description:

Thus, the current data confirmed that circBNC2 sponged miR-217 to upregulate the HMGA2 level, thereby contributing to the HCC glycolysis and progression.
Other information
Title:

Circular RNA circBNC2 facilitates glycolysis and stemness of hepatocellular carcinoma through the miR-217/high mobility group AT-hook 2 (HMGA2) axis.

Journal: Heliyon
Published: 2023/6/26
PubMed ID: 37360090