circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: circRNA_0000284
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 3393
DO name: coronary artery disease
Disease details: coronary heart disease
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ETS1
Associated microRNA: hsa-miR-338-3p
Biological function: Consistent with the results of cell transfection experiments and luciferase assays, Western blotting showed that hsa_circRNA_0000284 plays a role in the regulation of hsa-miRNA-338-3p expression. Subsequently, hsa-miRNA-338-3p was found to be involved in the regulation of ETS1 expression
Molecular mechanism: -
Survival: -
Supported No.:
 2
Description:

The expression of hsa_circRNA_0000284 affected proliferation, cycle distribution, aging, and apoptosis in EA-hy926 cells.
Other information
Title:

Hsa_circRNA_0000284 acts as a ceRNA to participate in coronary heart disease progression by sponging miRNA-338-3p via regulating the expression of ETS1.

Journal: J Biomol Struct Dyn
Published: 2023/6/19
PubMed ID: 37334706