circRNA basic information
circBase ID: -
Name: hsa_circ_SH3PXD2A
Synonym: circSH3PXD2A
Host Gene: hsa-miR-375-3p
 
 
 
Disease basic information
DO ID:
 5409
DO name: lung small cell carcinoma
Disease details: small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SCLC cell line (SBC-3, H446, H69, H82, SHP77)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: YAP1
Associated microRNA: hsa-miR-375-3p
Biological function: CircSH3PXD2A inhibited the chemoresistance, proliferation, migration, and invasion of SCLC cells
Molecular mechanism: circSH3PXD2A/hsa-miR-375-3p/YAP1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Our results manifest that EVs-derived circSH3PXD2A inhibits the chemoresistance of SCLC through miR-375-3p/YAP1 axis.
Other information
Title:

Extracellular Vesicles Derived circSH3PXD2A Inhibits Chemoresistance of Small Cell Lung Cancer by miR-375-3p/YAP1.

Journal: Int J Nanomedicine
Published: 2023/6/12
PubMed ID: 37304971