circRNA basic information
circBase ID: hsa_circ_0000119
Name: hsa_circ_MAN1A2
Synonym: circMAN1A2
Host Gene: hsa-miR-940
 
 
 
Disease basic information
DO ID:
 9261
DO name: nasopharynx carcinoma
Disease details: nasopharyngeal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human NPC cell lines (5-8F, HK-1, NP69)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ERBB2
Associated microRNA: hsa-miR-940
Biological function: -
Molecular mechanism: circMAN1A2/hsa-miR-940/ERBB2 axis, miRNA sponge, PI3K/AKT/mTOR signaling pathway
Survival: -
Supported No.:
 2
Description:

Taken together, the present findings suggest that circMAN1A2 promotes VM formation and progression of NPC through miR-940/ERBB2 axis and further activates the PI3K/AKT/mTOR pathway.
Other information
Title:

CircMAN1A2 promotes vasculogenic mimicry of nasopharyngeal carcinoma cells through upregulating ERBB2 via sponging miR-940.

Journal: Oncol Res
Published: 2023/6/12
PubMed ID: 37304410