circRNA basic information
circBase ID: hsa_circ_0000069
Name: hsa_circ_STIL
Synonym: circ_0000069
Host Gene: hsa-miR-432
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: breast cancer cell lines (BT549, MCF-7, SK-BR-3, T47D_MDA-MB-231), normal mammary epithelial cell (MCF10A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-432
Biological function: After silencing has_circ_0000069 in breast cancer cells, its expression reduced, and the ability of cell proliferation, migration, and invasion decreased
Molecular mechanism: Breast cancer cell lines (BT549, MCF-7, SK-BR-3, T47D, MDA-MB-231), and normal mammary epithelial cell (MCF-10A)
Survival: better
Supported No.:
 1
Description:

These findings revealed that has_circ_0000069 may be a biomarker for predicting prognosis and a therapeutic target for treating patients with breast cancer.
Other information
Title:

Has_circ_0000069 expression in breast cancer and its influences on prognosis and cellular activities.

Journal: Oncol Res
Published: 2023/6/12
PubMed ID: 37303741