circRNA basic information
circBase ID: hsa_circ_0059457
Name: hsa_circ_TASP1
Synonym: circ_0059457
Host Gene: hsa-miR-140-3p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human normal breast epithelial cells (MCF10A), BC cells (MB231, BT549)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: UBE2C
Associated microRNA: hsa-miR-140-3p
Biological function: Circ_0059457 knockdown inhibited BC cell proliferation, metastasis, sphere formation ability, and glycolysis. In terms of mechanism
Molecular mechanism: Circ_0059457/hsa-miR-140-3p/UBE2C axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0059457 promoted BC progression via miR-140-3p/UBE2C axis, which provided potential target for the treatment of BC.
Other information
Title:

Circ_0059457 Promotes Proliferation, Metastasis, Sphere Formation and Glycolysis in Breast Cancer Cells by Sponging miR-140-3p to Regulate UBE2C.

Journal: Biochem Genet
Published: 2023/6/7
PubMed ID: 37284894