circRNA basic information
circBase ID: hsa_circ_0064559
Name: hsa_circ_KCNH8
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: CRC cell lines (RKO, SW620)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: STAT1, ATF2, TNFRSF10B, TGFBR2, BAX, SQSTM1, SLC4A7, CD274
Associated microRNA: -
Biological function: The proliferation of CRC cell lines was decreased, while the proportion of apoptotic and G1 phase cells was higher after hsa_circ_0064559 knockdown. In vivo xenograft nude mice model revealed that the volume and weight of the tumor were reduced by hsa_circ_0064559 knockdown.
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

The hsa_circ_0064559 may be a potential biomarker for early diagnosis or prognosis of CRC and a novel drug target for CRC therapy.
Other information
Title:

Circular RNA hsa_circ_0064559 affects tumor cell growth and progression of colorectal cancer.

Journal: World J Surg Oncol
Published: 2023/6/7
PubMed ID: 37280630