circRNA basic information
circBase ID: hsa_circ_0104206
Name: hsa_circ_CSNK1G1
Synonym: Circ_0104206
Host Gene: hsa-miR-188-3p
 
 
 
Disease basic information
DO ID:
 219
DO name: colon cancer
Disease details: colon cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CCNA2
Associated microRNA: hsa-miR-188-3p
Biological function: Circ_0104206 silencing repressed CC cell proliferative and migratory behaviors, and also decelerated tumor development in animal models. MiR-188-3p was directly targeted by circ_0104206, and its inhibitor had the ability to reverse the anticancer effects of circ_0104206 silencing on CC cells.
Molecular mechanism: Circ_0104206/hsa-miR-188-3p/CCNA2 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

In conclusion, Circ_0104206 plays oncogenic roles in CC via the implication of miR-188-3p/CCNA2 network, which further discloses CC pathogenesis and supplies potential markers for CC.
Other information
Title:

Hsa_Circ_0104206 is An Oncogenic circRNA in Colon Cancer by Targeting Mir-188-3p/CCNA2 Axis.

Journal: Horm Metab Res
Published: 2023/6/6
PubMed ID: 37276868