circRNA basic information
circBase ID: hsa_circ_0003356
Name: hsa_circ_PPP5C
Synonym: circ_0003356
Host Gene: hsa-miR-668-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: GES-1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: SOCS3
Associated microRNA: hsa-miR-668-3p
Biological function: Exogenous circ_0003356 expression and miR-668-3p silencing suppressed the migration, viability, proliferation, epithelial to mesenchy-mal transition (EMT) and invasion of GC cells and enhanced apoptosis. Circ_0003356 overexpression impaired tumor growth in xenograft mice
Molecular mechanism: circ_0003356/hsa-miR-668-3p/SOCS3 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0003356 impaired GC development through its interaction with the miR-668-3p/SOCS3 axis.
Other information
Title:

Circ_0003356 suppresses gastric cancer growth through targeting the miR-668-3p/SOCS3 axis.

Journal: World J Gastrointest Oncol
Published: 2023/6/5
PubMed ID: 37275445