circRNA basic information
circBase ID: hsa_circ_0005785
Name: hsa_circ_ANAPC7
Synonym: circ_0005785
Host Gene: hsa-miR-640
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GSK3beta
Associated microRNA: hsa-miR-640
Biological function: circ_0005785 knockdown hindered proliferation, migration, invasion, angiogenesis, and boosted apoptosis in PTX-treated HCC cells in vitro. circ_0005785 silencing improved the PTX sensitivity of HCC in vivo
Molecular mechanism: circ_0005785/hsa-miR-640/GSK3beta axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

PTX restrained HCC tumorigenesis partly via regulating the circ_0005785/miR-640/GSK3beta axis, hinting at a promising therapeutic target for the HCC treatment.
Other information
Title:

Paclitaxel inhibits hepatocellular carcinoma tumorigenesis by regulating the circ_0005785/miR-640/GSK3beta.

Journal: Cell Biol Int
Published: 2023/6/3
PubMed ID: 37269228