circRNA basic information
circBase ID: hsa_circ_0024107
Name: hsa_circ_MMP1
Synonym: circ_0024107
Host Gene: hsa-miR-5572, hsa-miR-6855-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: bone marrow-derived MSCs (BM-MSCs), GC-MSCs, gastric cancer cell lines (AGS, HGC-27)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: CPT1A
Associated microRNA: hsa-miR-5572, hsa-miR-6855-5p
Biological function: circ_0024107 was identified to mediate GC_MSCs to promote gastric cancer lymphatic metastasis by inducing fatty acid oxidation (FAO) metabolic reprogramming
Molecular mechanism: circ_0024107/miR_5572, hsa-miR-6855_5p/CPT1A axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Taken together, the findings of the present study suggest the crucial role of FAO metabolic reprogramming mediated by GC_MSC_derived circ_0024107 in synergistically promoting gastric cancer lymphatic metastasis via miR_5572/6855_5p_CPT1A signaling.
Other information
Title:

GC_MSC_derived circ_0024107 promotes gastric cancer cell lymphatic metastasis via fatty acid oxidation metabolic reprogramming mediated by the miR_5572/6855_5p/CPT1A axis.

Journal: Oncol Rep
Published: 2023/6/2
PubMed ID: 37264961