circRNA basic information
circBase ID: hsa_circ_0001361
Name: hsa_circ_FNDC3B
Synonym: circRNA-0001361
Host Gene: hsa-miR-491
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MCF-7 as well as MDA-MB-231 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FGFR4
Associated microRNA: hsa-miR-491
Biological function: -
Molecular mechanism: circRNA-0001361/hsa-miR-491/FGFR4 axis, miRNA sponge
Survival: poor
Supported No.:
 1
Description:

Our study suggested that the up-regulation of hsa_circRNA-0001361 could up-regulate the expression of FGFR4 via sponging the expression of miR-491-5p, resulting in the alleviated axillary response after neoadjuvant chemotherapy (NAC) in breast cancer.
Other information
Title:

The circRNA-0001361/miR-491/FGFR4 axis is associated with axillary response evaluated by ultrasound following NAC in subjects with breast cancer.

Journal: Biochem Biophys Rep
Published: 2023/5/30
PubMed ID: 37250983