circRNA basic information
circBase ID: hsa_circ_0030018
Name: hsa_circ_POSTN
Synonym: circ0030018
Host Gene: hsa-miR-1236
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal glial cell (HEB), glioma cells (U87, U251, SHG44, T98, SF767)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HER2
Associated microRNA: hsa-miR-1236
Biological function: Colony formation, CCK-8, and transwell assay made clear that circ0030018 silencing dramatically cut down glioma growth and invasion
Molecular mechanism: circ0030018/hsa-miR-1236/HER2 axis, miRNA sponge
Survival: -
Supported No.:
 5
Description:

In conclusion, our study investigated the roles and mechanisms of the ISL on the circ0030018/miR-1236/HER2 pathway in glioma tumorigenesis and progression.
Other information
Title:

Isoliquiritigenin inhibits circ0030018 to suppress glioma tumorigenesis via the miR-1236/HER2 signaling pathway.

Journal: MedComm (2020)
Published: 2023/5/30
PubMed ID: 37250146