circRNA basic information
circBase ID: hsa_circ_0001955
Name: hsa_circ_CSNK1G1
Synonym: circ0001955
Host Gene: hsa-miR-188-3p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human cervical cancer cell line SiHa (HPV 16_+), a normal cervical cell line (HcerEpic)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NCAPG2
Associated microRNA: hsa-miR-188-3p
Biological function: The overexpression of circ0001955 promotes tumor proliferation and metastasis, whereas the knockdown of circ0001955 exerts the opposite effects
Molecular mechanism: AKT/mTOR signaling pathway, circ0001955/hsa-miR-188-3p/NCAPG2 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ0001955 promotes CSCC tumorigenesis and metastasis via the miR-188-3p/NCAPG2 axis which would provide an opportunity to search new therapeutic targets for CSCC.
Other information
Title:

Circular RNA circ0001955 promotes cervical cancer tumorigenesis and metastasis via the miR-188-3p/NCAPG2 axis.

Journal: J Transl Med
Published: 2023/5/30
PubMed ID: 37248471