circRNA basic information
circBase ID: -
Name: hsa_circ_BBS9
Synonym: circBBS9
Host Gene: hsa-miR-485-3p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Osteoblast cell line (hFOB 1.19, HOS, U2OS, Saos2, MG63)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGB1
Associated microRNA: hsa-miR-485-3p
Biological function: the knockdown of circBBS9 negatively impacted the migration, proliferation and invasion of osteosarcoma cells
Molecular mechanism: circBBS9/hsa-miR-485-3p/HMGB1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

The findings explained that CircBBS9 promoted the malignant osteosarcomas progression by sponging miR-485-3p/HMGB1 and proposed CircBBS9 as a prognostic biomarker and therapeutic candidate for osteosarcoma patients.
Other information
Title:

CircBBS9 accelerates the malignant progression of osteosarcoma through sponging miR-485-3p/HMGB1 axis.

Journal: J Orthop Sci
Published: 2023/5/30
PubMed ID: 37248151