circRNA basic information
circBase ID: hsa_circ_0001238
Name: hsa_circ_CCDC134
Synonym: circCCDC134
Host Gene: hsa-miR-625-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human NSCLC cells (H1299, HCC827, PC9, A549), a normal bronchial epithelial cell line (BEAS-2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NFAT5
Associated microRNA: hsa-miR-625-5p
Biological function: Downregulated circCCDC134 restrained NSCLC cell growth, metastasis and glycolysis
Molecular mechanism: circCCDC134/iR-625-5p/NFAT5 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Our study revealed that circCCDC134 was involved in regulating NSCLC progression through the miR-625-5p/NFAT5 pathway, confirming that circCCDC134 might function as the diagnostic and therapeutic target for NSCLC.
Other information
Title:

A novel molecular mechanism mediated by circCCDC134 regulates non-small cell lung cancer progression.

Journal: Thorac Cancer
Published: 2023/5/26
PubMed ID: 37231545