circRNA basic information
circBase ID: hsa_circ_0007203
Name: hsa_circ_DLG1
Synonym: circDLG1
Host Gene: hsa-miR-141-3p
 
 
 
Disease basic information
DO ID:
684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: A normal liver cell line (LO2)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: WTAP
Associated microRNA: hsa-miR-141-3p
Biological function: Knockdown of circDLG1 and miR-141-3p mimic could inhibit the tumorigenesis of HCC cells in vivo and in vitro
Molecular mechanism: circDLG1/hsa-miR-141-3p/WTAP axis, miRNA sponge
Survival: poor
Supported No.:
3
Description:

circDLG1 participates in the progression of HCC cells by sponging miR-141-3p with WTAP, providing new insight into the treatment of HCC.

Other information
Title:

Circular RNA circDLG1 contributes to HCC progression by regulating the miR-141-3p/WTAP axis.

Journal: Funct Integr Genomics
Published: 2023/5/25
PubMed ID: 37227531