circRNA basic information
circBase ID: hsa_circ_0001982
Name: hsa_circ_RNF111
Synonym: circ-RNF111
Host Gene: hsa-miR-361-5p
 
 
 
Disease basic information
DO ID:
 4866
DO name: salivary gland adenoid cystic carcinoma
Disease details: salivary adenoid cystic carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SACC cell lines (SACC-LM, SACC-83), human submandibular gland cell line (HSG), neural cell line microglia (BV2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGB2
Associated microRNA: hsa-miR-361-5p
Biological function: reduction of circ-RNF111 suppressed PNI in a SACC xenograft model
Molecular mechanism: circ-RNF111/hsa-miR-361-5p/HMGB2 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Taken together, circ-RNF111 stimulates PNI in SACC by miR-361-5p/HMGB2 axis and may serve as a potential therapeutic target for SACC.
Other information
Title:

Induction of perineural invasion in salivary adenoid cystic carcinoma by circular RNA RNF111.

Journal: Clin Transl Oncol
Published: 2023/5/24
PubMed ID: 37222950