circRNA basic information
circBase ID: hsa_circ_0001006
Name: hsa_circ_RTN4
Synonym: circ_0001006
Host Gene: hsa-miR-424-5p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human-sourced TNBC cell lines (MDA-MB-231, BT-549, HCC-1937, MDA-MB-468), normal human breast cell (MCF-10 A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-424-5p
Biological function: silencing circ_0001006 suppressed cell proliferation, migration, and invasion
Molecular mechanism: -
Survival: poor
Supported No.:
 2
Description:

Upregulated circ_0001006 in TNBC served as a poor prognosis predictor and tumor promoter via negatively regulating miR-424-5p.
Other information
Title:

circRNA_0001006 predicts prognosis and regulates cellular processes of triple-negative breast cancer via miR-424-5p.

Journal: Cell Div
Published: 2023/5/17
PubMed ID: 37194024