circRNA basic information
circBase ID: -
Name: hsa_circ_RNA7632
Synonym: circRNA7632
Host Gene: -
 
 
 
Disease basic information
DO ID:
 13378
DO name: Kawasaki disease
Disease details: kawasaki disease
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Primary HUVECs
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: IL-33
Associated microRNA: -
Biological function: Overexpression of circ7632 significantly increased vimentin and alpha-SMA expression, decreased ZO-1 expression, and also decreased cell proliferation. Down-regulation of circ7632 expression got the opposite results
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Circ7632 down-regulation could alleviate EndoMT likely through decreasing IL-33 expression. The circ7632 may become a potential therapeutic target for KD.
Other information
Title:

CircRNA7632 down-regulation alleviates endothelial cell dysfunction in Kawasaki disease via regulating IL-33 expression.

Journal: Cell Stress Chaperones
Published: 2023/5/11
PubMed ID: 37166618