The results of qPCR assay showed that five (mmu_circRNA_017963, mmu_circRNA_003540, mmu_circRNA_013699, mmu_circRNA_012180 and mmu_circRNA_006173) out of the six circRNAs significantly differed between the hippocampal tissues of 10-month-old SAMP8 and age-matched SAMR1.
Comprehensive analysis of differentially expressed profiles of Alzheimer disease associated circular RNAs in an Alzheimer disease mouse model.