circRNA basic information
circBase ID: hsa_circ_0088036
Name: hsa_circ_SUSD1
Synonym: circ_0088036
Host Gene: hsa-miR-1343-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: Bcl-3
Associated microRNA: hsa-miR-1343-3p
Biological function: hsa_circ_0088036 silencing inhibited proliferative, invasive, and migrative potential of NSCLC cells
Molecular mechanism: circ_0088036/hsa-miR-1343-3p/Bcl-3 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

In conclusion, hsa_circ_0088036 functions as an oncogene by targeting the miR-1343-3p/Bcl-3 axis via TGFbeta/Smad3/EMT signaling pathway.
Other information
Title:

Hsa_circ_0088036 promotes nonsmall cell lung cancer progression by regulating miR-1343-3p/Bcl-3 axis through TGFbeta/Smad3/EMT signaling.

Journal: Mol Carcinog
Published: 2023/5/3
PubMed ID: 37132942