circRNA basic information
circBase ID: hsa_circ_0001387
Name: hsa_circ_WHSC1
Synonym: circ_0001387
Host Gene: hsa-miR-136-5p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human normal mammary epithelial cell line (MCF-10A), BC cell lines (MCF-7, MDA-MB-231, MDA-MB-468)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SKA2
Associated microRNA: hsa-miR-136-5p
Biological function: the downregulation of circ_0001387 restrained BC cell progression in vitro and in vivo
Molecular mechanism: circ_0001387/hsa-miR-136-5p/SKA2 axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

Our study indicated that circ_0001387 contributed to BC cell progression through miR-136-5p/SKA2 axis.
Other information
Title:

Circ_0001387 regulates SKA2 to accelerate breast cancer progression through miR-136-5p.

Journal: Thorac Cancer
Published: 2023/5/3
PubMed ID: 37132052