circRNA basic information
circBase ID: hsa_circ_0069982
Name: hsa_circ_MTHFD2L
Synonym: circMTHFD2L
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: GC cell lines (HGC-27, MGC-803, MKN-28, MKN-45, AGS, SGC-7901), HEK-293T cells
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: SET, AKT
Associated microRNA: -
Biological function: CM-248aa, instead of circMTHFD2L suppressed the proliferation and metastasis of GC in vitro and in vivo
Molecular mechanism: -
Survival: better
Supported No.:
 1
Description:

Our discovery revealed that CM-248aa could be a potential prognostic biomarker and endogenous therapeutic option for GC.
Other information
Title:

Circular MTHFD2L RNA-encoded CM-248aa inhibits gastric cancer progression by targeting the SET-PP2A interaction.

Journal: Mol Ther
Published: 2023/4/27
PubMed ID: 37101395