circRNA basic information
circBase ID: hsa_circ_0028899
Name: hsa_circ_RNF10
Synonym: circRNF10
Host Gene: -
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: BC cell lines (MDA-MB-231, MCF-7, MDA-MB-468, BT549), non-tumorigenic breast epithelial cell line (MCF-10A, HEK293T)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: DHX15
Associated microRNA: -
Biological function: CircRNF10 inhibited the proliferation and migration of BC
Molecular mechanism: circRNF10/DHX15/p65 axis, NF-KB pathway
Survival: better
Supported No.:
 3
Description:

CircRNF10-DHX15 interaction suppressed the DHX15-NF-kB p65 positive feedback loop, thereby inhibiting BC progression.
Other information
Title:

CircRNF10-DHX15 interaction suppressed breast cancer progression by antagonizing DHX15-NF-kappaB p65 positive feedback loop.

Journal: Cell Mol Biol Lett
Published: 2023/4/27
PubMed ID: 37101128