circRNA basic information
circBase ID: hsa_circ_0060967
Name: hsa_circ_RAE1
Synonym: circ_0060967
Host Gene: hsa-miR-1184
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HCT-116, SW480 CRC cells, normal HCO cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SRC
Associated microRNA: hsa-miR-1184
Biological function: Decreased expression of circ_0060967 could suppress cell growth, motility, and invasiveness of CRC cells in vitro and tumor growth in vivo
Molecular mechanism: circ_0060967/hsa-miR-1184/SRC axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

This study demonstrates a novel circ_0060967/miR-1184/SRC regulatory cascade in affecting CRC cell malignant behaviors, which can have a broad effect on the field of molecularly targeted therapeutics.
Other information
Title:

Circ_0060967 contributes to colorectal cancer progression by sponging miR-1184 to up-regulate SRC proto-oncogene.

Journal: Arab J Gastroenterol
Published: 2023/4/13
PubMed ID: 37045727