circRNA basic information
circBase ID: -
Name: hsa_circ_FAM114A2
Synonym: circFAM114A2
Host Gene: hsa-miR-630
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human HCC cell lines (Huh7, MHCC97H, MHCC97L, HCCLM3, HepG2, Hep3B), human embryonic kidney cells (293_T)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: HHIP
Associated microRNA: hsa-miR-630
Biological function: circFAM114A2 overexpression significantly blunted HCC cell proliferation, migration, invasion, and promoted apoptosis, whereas circFAM114A2 silencing posed opposite effects
Molecular mechanism: circFAM114A2/hsa-miR-630/HHIP axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

CircFAM114A2 exerts a tumor suppressor role in HCC through miR-630/HHIP axis, and may be served as a potential diagnostic and therapeutic biomarker for HCC patients.
Other information
Title:

CircFAM114A2 inhibits the progression of hepatocellular carcinoma via miR-630/HHIP axis.

Journal: Cancer Med
Published: 2023/4/12
PubMed ID: 37039160