circRNA basic information
circBase ID: hsa_circ_0001633
Name: hsa_circ_SOBP
Synonym: circSOBP
Host Gene: hsa-miR-200a-3p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human cell lines (T24, EJ, 253J, 5637), immortalized normal uroepithelium cell line (SV-HUC-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PTEN
Associated microRNA: hsa-miR-200a-3p
Biological function: Overexpressed circSOBP suppressed cell proliferation, migration, and invasion both in vitro and in vivo
Molecular mechanism: circSOBP/hsa-miR-200a-3p/PTEN axis, miRNA sponge
Survival: better
Supported No.:
 1
Description:

Overall, circSOBP inhibits BCa tumorigenesis and metastasis by a novel miR-200a-3p/PTEN axis, which makes it an excellent biomarker and therapeutic target for treating BCa.
Other information
Title:

circSOBP Inhibits Bladder Cancer Proliferation and Metastasis by Regulating the miR-200a-3p/PTEN Axis and Participating in the Immune Response.

Journal: Cell Transplant
Published: 2023/4/8
PubMed ID: 37026617