circRNA basic information
circBase ID: hsa_circ_0070661
Name: hsa_circ_CCDC109B
Synonym: circ_0070661
Host Gene: hsa-miR-556-5p
 
 
 
Disease basic information
DO ID:
 3910
DO name: lung adenocarcinoma
Disease details: lung adenocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: LUAD cell lines (H1650, A549 ), human bronchial epithelial cell line (BEAS-2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: TEK
Associated microRNA: hsa-miR-556-5p
Biological function: Hsa_circ_0070661 upregulation restrained the viability, migration and tumor growth of LUAD cells, and promoted apoptosis
Molecular mechanism: circ_0070661/hsa-miR-556-5p/TEK axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Hsa_circ_0070661 sponges miR-556-5p to inhibit LUAD development via regulating TEK, providing a promising molecular target for LUAD clinical therapy.
Other information
Title:

Hsa_circ_0070661 inhibits cancer progression through miR-556-5p/TEK axis in lung adenocarcinoma.

Journal: Cancer Biomark
Published: 2023/4/4
PubMed ID: 37005879