circRNA basic information
circBase ID: hsa_circ_0001445
Name: hsa_circ_SMARCA5
Synonym: circ_0001445
Host Gene: hsa-miR-507, hsa-miR-375-3p, hsa-miR-942-5p
 
 
 
Disease basic information
DO ID:
 3393
DO name: coronary artery disease
Disease details: coronary heart disease
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-507, hsa-miR-375-3p, hsa-miR-942-5p
Biological function: Positive correlations were evident between hsa_circ_0001445 expression level and the levels of hemoglobin, triglycerides, high- and low-density lipoprotein cholesterol. A significant negative correlation was also found between hsa_circ_0001445 expression level and age and the neutrophil level. Low expression of hsa_circ_0001445 exhibited a discriminatory ability between CHD patients and healthy controls
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

The hsa_circ_0001445 level in peripheral blood leukocytes may serve as a biomarker for CHD diagnosis. Our work on circRNA-miRNA-mRNA networks suggests a potential role for hsa_circ_0001445 in CHD development.
Other information
Title:

Identification of hsa_circ_0001445 of a novel circRNA-miRNA-mRNA regulatory network as potential biomarker for coronary heart disease.

Journal: Front Cardiovasc Med
Published: 2023/4/1
PubMed ID: 36998978