circRNA basic information
circBase ID: hsa_circ_0017842
Name: hsa_circ_FAM188A
Synonym: circ_0017842
Host Gene: hsa-miR-1294
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SPARC
Associated microRNA: hsa-miR-1294
Biological function: Upregulating hsa_circ_0017842 in GC cells led to an increase in their proliferation, migration and invasion, and hsa_circ_0017842 knockdown showed the opposite effects on GC cells
Molecular mechanism: hsa_circ_0017842/hsa-miR-1294/SPARC axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Overall, this study confirmed that hsa_circ_0017842 acted as a ceRNA to promote the malignancy of GC cells through regulating the miR-1294/SPARC axis.
Other information
Title:

hsa_circ_0017842 acts as a competing endogenous RNA to enhance the malignancy of gastric cancer.

Journal: Adv Clin Exp Med
Published: 2023/3/31
PubMed ID: 36994684