circRNA basic information
circBase ID: hsa_circ_0000251
Name: hsa_circ_IDE
Synonym: circIDE
Host Gene: hsa-miR-19b-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human HCC cell lines (SMMC-7721, Huh7, Hep3B, HepG2), human hepatic cell line (LO2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RBMS1
Associated microRNA: hsa-miR-19b-3p
Biological function: -
Molecular mechanism: circIDE/hsa-miR-19b-3p/RBMS1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Collectively, our findings established circIDE/miR-19b-3p/RBMS1 axis as a regulator of ferroptosis, which could be a promising therapeutic target and prognostic factor.
Other information
Title:

Suppressing circIDE/miR-19b-3p/RBMS1 axis exhibits promoting-tumour activity through upregulating GPX4 to diminish ferroptosis in hepatocellular carcinoma.

Journal: Epigenetics
Published: 2023/3/30
PubMed ID: 36989117