circRNA basic information
circBase ID: hsa_circ_0008035
Name: hsa_circ_EXT1
Synonym: circ_0008035
Host Gene: hsa-miR-1184
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human ureteral epithelial cells (SV-HUC-1), human BC cell lines (5,637, T24), human umbilical vein endothelial cells (HUVECs)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RAP2B
Associated microRNA: hsa-miR-1184
Biological function: Circ_0008035 knockdown constrained cell proliferation, migration, invasion and angiogenesis but promoted apoptosis in vitro. And circ_0008035 silencing curbed xenograft tumor growth in vivo
Molecular mechanism: circ_0008035/hsa-miR-1184/RAP2B axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

Circ_0008035-mediated BC progression via regulating the miR-1184/RAP2B axis, providing a potential target for BC treatment.
Other information
Title:

Hsa_circ_0008035 Knockdown Inhibits Bladder Cancer Progression through miR-1184/RAP2B Axis.

Journal: Urol Int
Published: 2023/3/24
PubMed ID: 36958293