circRNA basic information
circBase ID: hsa_circ_0000212
Name: hsa_circ_SFMBT2
Synonym: circ_0000212
Host Gene: hsa-miR-1236-3p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Cervical cancer cell lines (SiHa, C33A), human umbilical vein endothelial cells (HUVECs)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GREM1
Associated microRNA: hsa-miR-1236-3p
Biological function: Silencing of endogenous circ_0000212 hindered cancer cell proliferation, motility and invasion and induced apoptosis, as well as diminished the tube formation of human umbilical vein endothelial cells (HUVECs) in vitro
Molecular mechanism: circ_0000212/hsa-miR-1236-3p/GREM1 axis, miRNA sponge
Survival: -
Supported No.:
 3
Description:

Our findings identify a novel ceRNA regulatory network, circ_0000212/miR-1236-3p/GREM1 axis, in cervical carcinogenesis, and provide potential targets that can be explored for therapeutic interventions.
Other information
Title:

Regulation of Cervical Cancer Development by a Novel Circ_0000212/miR-1236-3p/GREM1 ceRNA Crosstalk.

Journal: Mol Biotechnol
Published: 2023/3/24
PubMed ID: 36952219