circRNA basic information
circBase ID: hsa_circ_0000479
Name: hsa_circ_EPSTI1
Synonym: circ_0000479
Host Gene: hsa-miR-766
 
 
 
Disease basic information
DO ID:
 7148
DO name: rheumatoid arthritis
Disease details: rheumatoid arthritis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: RA-FLSs (MH7A cells), normal FLSs (primary cells)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FKBP5
Associated microRNA: hsa-miR-766
Biological function: circ_0000479 knockdown suppressed pathogenic properties of RA-FLSs
Molecular mechanism: circ_0000479/hsa-miR-766/FKBP5 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

In summary, circ_0000479 binds to miR-766 to promote RA progression via FKBP5.
Other information
Title:

Circ_0000479 promotes proliferation, invasion, migration and inflammation and inhibits apoptosis of rheumatoid arthritis fibroblast-like synoviocytes via miR-766/FKBP5 axis.

Journal: J Orthop Surg Res
Published: 2023/3/22
PubMed ID: 36941600